A Secret Weapon For ceesdekker.net
A Secret Weapon For ceesdekker.net
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Nanotechnology gives A selection of prospects to add to biology. In this article I'll existing illustrations where nanofabrication – the chance to make confined structures with dimensions at will – is employed to examine the biophysics of solitary molecules and cells. I'll current some examples from our lab:
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Again in 1991, Sumio Iijima on the NEC Corporation had documented the synthesis of carbon nanotubes. Band composition calculations suggested that these nanotubes could exhibit metallic band conduction. This would be a substantial benefit above the conducting polymers we had explored, which were, in fact, disordered semiconductors supplying just variable-selection hopping conductivity.
Regretably, For a long time after Iijima’s report, the manufacture of thoroughly clean nanotubes was cumbersome. In 1996, nevertheless, the team of Richard Smalley at Rice College managed to provide solitary-walled carbon nanotubes at high produce. Shortly soon after, I contacted Smalley, and we made a decision to be a part of forces to evaluate the transportation through a solitary carbon nanotube.
This yielded a breakthrough. Within just only a few months, we were being in the position to measure transportation via somebody single-walled carbon nanotube. Based upon minimal-temperature experiments by a superb PhD pupil in my team, Sander Tans (now a valued colleague and professor at Delft University of Technological innovation with the Energetic research lab at AMOLF in Amsterdam), we showed that carbon nanotubes were being real quantum wires with pretty extended (micrometres) Digital coherence lengths — confirming theoretical predictions of metallic conduct.
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van ceesdekker 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
Considering the fact that 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling scientific studies of nucleosomes and DNA restore proteins to DNA translocation through nanopores. A short while ago his exploration has focused on researching mobile division with germs on chip, while his best curiosity is in the course of acknowledging synthetic cells.
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2003, demonstrated the main biosensors built outside of a carbon nanotube; solved the construction and mechanism of DNA repair proteins; and discovery of a completely new procedure for fabricating reliable-condition nanopores for DNA translocation
There was a person problem although — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule degree, conducting polymers had been truly not these kinds of good conductors, which was somewhat disappointing. We So broadened our view to test to uncover much more promising molecules.
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2001, discovery of solitary-electron transistors at area temperature based upon nanotubes; realization of to start with logic circuits with carbon nanotube equipment; and discovery of your molecular structure of DNA repair enzymes with AFM
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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)